staining with anti sv2 (Developmental Studies Hybridoma Bank)
Structured Review

Staining With Anti Sv2, supplied by Developmental Studies Hybridoma Bank, used in various techniques. Bioz Stars score: 97/100, based on 108 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/staining+with+anti+sv2/pmc13089715-151-13-16?v=Developmental+Studies+Hybridoma+Bank
Average 97 stars, based on 108 article reviews
Images
1) Product Images from "Dysregulated lactate metabolism synergizes with ALS genetic risk factors to accelerate motor decline"
Article Title: Dysregulated lactate metabolism synergizes with ALS genetic risk factors to accelerate motor decline
Journal: PLOS One
doi: 10.1371/journal.pone.0347135
Figure Legend Snippet: Motor function (latency to fall from an inverted screen) measured in 3-month-old WT, TDP43 Q331K/+ , LDHB MNKO and TDP43 Q331K/+ ; LDHB MNKO mice (A), electrophysiological recording performed on 3-month-old animals to determine the difference in CMAP at the ankle and sciatic notch ( B & C ) and Sensory Nerve Action Potential (SNAP) at the tail (n = 10-12) (D). NMJs on lumbrical muscles stained with anti-NF, anti-SV2 and BTX to compare innervation of 3-month-old mice of different genotypes (n = 3; statistical comparison is between fully innervated endplates). Statistical significance was determined by pairwise Fisher’s exact tests on raw counts, with a Bonferroni correction applied for multiple comparisons. (E-I). Spinal cords stained to detect TDP43 and nuclei (DAPI) indicate no mislocalization in 6-month-old LDHB MNKO; TDP43 Q331K/+ or LDHB MNKO mice (J & K) . Representative images of 40x and 63x toluidine blue-stained sections of tibial nerves from 3-month-old animals (L-O) . Average g-ratio indicates no difference in degeneration between genotypes (n = 3). Unless otherwise mentioned, all statistical significance was determined by one-way ANOVA with Tukey’s multiple comparisons test (P) . ***p < 0.001, **p < 0.01.
Techniques Used: Muscles, Staining, Comparison